Cyclopropanecarboxylic Acid CAS 1759-53-1

1. Cyclopropanecarboxylic acid is a versatile organic intermediate used extensively in the synthesis of pharmaceuticals and agrochemicals . It is a key building block for producing antibacterial drugs like fluoroquinolones (e.g., cyclopropane fluoropiperazinic acid) and for synthesizing pyrethroid insecticides .
2. The compound serves as a reagent in pharmaceutical research, for instance, in the synthesis of potent PARP-1 inhibitors and HCV replication inhibitors .Cyclopropanecarboxylic acid CAS 1759-53-1 also functions as an annulation reagent in organic synthesis for converting aromatics to 2-methylindanones .
3. Applications of Cyclopropanecarboxylic acid also include its use in developing polymer additives, coatings, adhesives, and surfactants .

1. Store Cyclopropanecarboxylic acid in a tightly sealed container in a cool, dry, and well-ventilated place. Recommended storage temperatures are 0-6℃ or 2-8℃, and Cyclopropanecarboxylic acid CAS 1759-53-1 must be protected from light and heat .
2. Keep Cyclopropanecarboxylic acid strictly away from strong oxidizing agents, strong bases, and sources of ignition due to its combustible nature and incompatibility with these materials .
3. Always use appropriate personal protective equipment (PPE) including chemical-resistant gloves, tightly fitting safety goggles, and protective clothing; use only with adequate ventilation or in a fume hood, as it is corrosive and causes burns .

1. Immediately isolate the spill area, eliminate all ignition sources, and ensure adequate ventilation. Contain Cyclopropanecarboxylic acid using inert, non-combustible absorbent material (e.g., dry sand) and prevent entry into drains or waterways .
2. Carefully collect Cyclopropanecarboxylic acid CAS 1759-53-1 using an explosion-proof vacuum or non-sparking tools, and place it into a sealed, labeled corrosion-resistant chemical waste container for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must wear full chemical-protective clothing including self-contained breathing apparatus (SCBA) during cleanup. Cyclopropanecarboxylic acid is classified for transport (UN 3265, Hazard Class 8, PG II) as a corrosive liquid .

1. Cyclopropanecarboxylic acid is classified as a corrosive substance (GHS signal word "Danger") causing severe skin burns and serious eye damage (H314). Cyclopropanecarboxylic acid CAS 1759-53-1 is also a combustible liquid (H227) and is harmful if swallowed (H302) .
2. Cyclopropanecarboxylic acid has a flash point of 72℃, a melting point of 14-19℃, and a boiling point of 182-184℃ . Its thermal decomposition or combustion produces toxic and irritating fumes including carbon oxides . Mouse intraperitoneal LD50 is 172 mg/kg .
3. Always consult Cyclopropanecarboxylic acid CAS 1759-53-1 the specific Safety Data Sheet (SDS) for Cyclopropanecarboxylic acid for complete hazard information, first-aid procedures (P301+P330+P331 for ingestion, P303+P361+P353 for skin, P305+P351+P338 for eyes), and handling instructions. Precautionary statements include P210 (keep away from heat), P260 (do not breathe vapors), and P280 (wear protective gloves/eye protection) .